Description

3-Pyridinecarboxylic Acid, 6-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Ethyl Ester is a high-purity, protected amino acid derivative featuring a pyridine core, designed for advanced synthetic applications. This compound is a critical building block in pharmaceutical research and development, offering a versatile handle for constructing complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for peptide synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key protected amino acid building block for the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce functionalized pyridine motifs into candidate molecules.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents and herbicides.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis (SPPS) as a Boc-protected nicotinic acid derivative.
• Ligand and Catalyst Development: Utilized for creating specialized ligands and organocatalysts due to its coordinating pyridine nitrogen and modifiable ester group.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and biochemical tools for studying biological pathways.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 6-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Ethyl Ester
CAS No.	169280-82-4
Molecular Formula	C14H20N2O4
Molecular Weight	280.32 g/mol
Synonyms	Ethyl 6-[(tert-Butoxycarbonyl)amino]nicotinate; 6-(Boc-amino)nicotinic Acid Ethyl Ester; Ethyl 6-((tert-Butoxycarbonyl)amino)pyridine-3-carboxylate; Boc-6-Aminonicotinic Acid Ethyl Ester; 6-(N-Boc-amino)nicotinic Acid Ethyl Ester; 6-[(tert-Butoxycarbonyl)amino]pyridine-3-carboxylic Acid Ethyl Ester; 6-Boc-Amino-3-pyridinecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 6-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot, ensuring traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The product is moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.