Description

3-Benzyl-1,3,8-Triaza-Spiro[4.5]Decane-2,4-Dione is a high-purity, synthetic organic compound belonging to the spirocyclic lactam class, serving as a critical advanced intermediate in modern pharmaceutical research and development. Its unique spiro-fused ring system provides a valuable three-dimensional scaffold for constructing novel bioactive molecules, particularly in the design of central nervous system (CNS) and enzyme-targeting drugs. This compound is essential for medicinal chemists and process development scientists in pharmaceutical and biotechnology companies seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: The structural motif is relevant for the development of inhibitors targeting specific enzymes.
• Chemical Biology Probes: Employed in the creation of molecular probes to study biological pathways and protein function.
• Process Chemistry & Scale-Up: Serves as a defined intermediate for optimizing synthetic routes from laboratory to pilot and commercial scale.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and research organizations for custom synthesis projects.

Basic Information

Product Name	3-Benzyl-1,3,8-Triaza-Spiro[4.5]Decane-2,4-Dione
CAS No.	169206-62-6
Molecular Formula	C₁₇H₂₁N₃O₂
Molecular Weight	299.37 g/mol
Synonyms	3-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione; 1,3,8-Triazaspiro[4.5]decane-2,4-dione, 3-benzyl-; 3-Benzyl-1,3,8-triazaspiro[4.5]decan-2,4-dione; Spiro[4.5]decane-2,4-dione, 3-benzyl-1,3,8-triaza-; 169206-62-6; 3-Benzyl-1,3,8-triaza-spiro[4.5]decan-2,4-dione
EINECS	Contact for details

Quality Control

Our 3-Benzyl-1,3,8-Triaza-Spiro[4.5]Decane-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment. We support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredient (API) starting materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.