Description

6-Chloropyridine-3-Carbohydrazide is a versatile heterocyclic building block and key synthetic intermediate. Its value lies in the reactive carbohydrazide functional group, which enables the construction of complex molecular architectures, particularly in the synthesis of nitrogen-containing heterocycles. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing pyridine and hydrazide pharmacophores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Chelating Agent Precursor: Serves as a starting material for the preparation of polydentate ligands used in catalysis and metal complexation.
• Heterocyclic Chemistry Research: A fundamental building block for constructing fused pyridine systems, such as pyrazoles, triazoles, and other N-heterocycles via cyclization reactions.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Used to develop molecular probes and inhibitors for studying enzymatic activity and biological pathways.

Basic Information

Product Name	6-Chloropyridine-3-Carbohydrazide
CAS No.	168893-66-1
Molecular Formula	C6H6ClN3O
Molecular Weight	171.58 g/mol
Synonyms	3-Hydrazinecarbonyl-6-chloropyridine; 6-Chloro-3-pyridinecarbohydrazide; 6-Chloronicotinohydrazide; 6-Chloropyridine-3-carboxylic acid hydrazide; (6-Chloropyridin-3-yl)carbohydrazide; 6-Chloro-3-pyridylcarbohydrazide; 6-Chloronicotinic acid hydrazide
EINECS	Contact for details

Quality Control

Our 6-Chloropyridine-3-Carbohydrazide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.