Description

2-(1,3-Benzodioxol-5-Yl)-8-Chloro-Imidazo[1,2-A]Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs) targeting the central nervous system. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel psychoactive pharmaceuticals and potential CNS drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Contract Research Organizations (CROs): Employed in custom synthesis and preclinical development projects.
• Academic Research: Serves as a substrate for studying heterocyclic chemistry and developing new synthetic methodologies.
• Biochemical Research: Potential use as a tool compound for probing biological pathways and receptor interactions.
• Agrochemical Intermediate: May be utilized in the research and development of new crop protection agents.

Basic Information

Product Name	2-(1,3-Benzodioxol-5-Yl)-8-Chloro-Imidazo[1,2-A]Pyridine
CAS No.	168837-41-0
Molecular Formula	C14H9ClN2O2
Molecular Weight	272.69 g/mol
Synonyms	8-Chloro-2-(1,3-benzodioxol-5-yl)imidazo[1,2-a]pyridine; 2-(Benzo[d][1,3]dioxol-5-yl)-8-chloroimidazo[1,2-a]pyridine; 8-Chloro-2-(3,4-methylenedioxyphenyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 8-chloro-2-(1,3-benzodioxol-5-yl)-; 168837-41-0; 2-(1,3-Benzodioxol-5-yl)-8-chloroimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 2-(1,3-Benzodioxol-5-Yl)-8-Chloro-Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.