Description

Methyl 2'-Methoxy[1,1'-Biphenyl]-3-Carboxylate is a high-purity biphenyl derivative ester, serving as a critical advanced pharmaceutical intermediate and versatile organic synthesis building block. Its unique molecular structure makes it particularly valuable for constructing complex molecules in medicinal chemistry. This compound is primarily utilized by pharmaceutical R&D and fine chemical synthesis sectors for developing active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex biphenyl scaffolds.
• Organic Synthesis Reagent: Used in cross-coupling reactions, esterification processes, and as a precursor for more complex carboxylic acid derivatives.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymeric materials due to its rigid biphenyl core.
• Agrochemical Synthesis: Intermediate in the production of certain high-performance pesticides and herbicides.
• Academic & Industrial R&D: Essential compound for research laboratories focusing on medicinal chemistry, synthetic methodology, and material science.

Basic Information

Product Name	Methyl 2'-Methoxy[1,1'-Biphenyl]-3-Carboxylate
CAS No.	168618-50-6
Molecular Formula	C16H16O4
Molecular Weight	272.30 g/mol
Synonyms	3-(2-Methoxybiphenyl-1-yl)methyl carboxylate; Methyl 3-(2'-methoxybiphenyl-1-yl)carboxylate; 2'-Methoxy[1,1'-biphenyl]-3-carboxylic acid methyl ester; Biphenyl-3-carboxylic acid, 2'-methoxy-, methyl ester; 1,1'-Biphenyl-3-carboxylic acid, 2'-methoxy-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2'-Methoxy[1,1'-Biphenyl]-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.