Description

Methyl 5-((tert-Butoxycarbonyl)Amino)Nicotinate is a high-purity, protected amino acid derivative and a key nicotinic acid-based building block. This compound is essential for the synthesis of complex molecules, offering a reactive ester group and a Boc-protected amine for selective deprotection and further functionalization. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates. Its defined structure ensures reproducibility and quality in advanced synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting nicotinic acid receptor pathways.
• Peptide Mimetic Synthesis: Used to incorporate modified amino acid units into peptide chains, creating analogs with enhanced stability or biological activity.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, or plant growth regulators with specific modes of action.
• Chemical Biology Probes: Employed in the construction of labeled compounds or affinity probes for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis services, enabling the production of tailored intermediates for client-specific projects.
• Academic & Institutional Research: Used in university and government laboratories for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Methyl 5-((tert-Butoxycarbonyl)Amino)Nicotinate
CAS No.	168618-38-0
Molecular Formula	C12H16N2O4
Molecular Weight	252.27 g/mol
Synonyms	5-((tert-Butoxycarbonyl)amino)nicotinic acid methyl ester; Methyl 5-[(tert-butoxycarbonyl)amino]pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester; Boc-5-Amino-nicotinic acid methyl ester; 5-(Boc-amino)nicotinic acid methyl ester; Methyl 5-(Boc-amino)nicotinate; 5-N-Boc-amino-nicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-((tert-Butoxycarbonyl)Amino)Nicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.