Description

Ethyl 2,2-Difluoro-3-Hydroxy-3-Methylbutanoate is a high-value fluorinated building block essential for advanced organic synthesis. This compound matters for its unique molecular architecture, featuring both a difluoromethyl group and a tertiary alcohol, which enables the precise introduction of fluorine atoms to modulate the biological activity and physicochemical properties of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in protease inhibitors and kinase modulators.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides where fluorine substitution enhances efficacy and environmental stability.
• Material Science Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers with tailored surface properties and chemical resistance.
• Fluorine Chemistry Research: An important reagent for studying new fluorination methodologies and constructing complex fluorinated scaffolds in academic and industrial labs.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated components for advanced display materials and dielectric fluids.

Basic Information

Product Name	Ethyl 2,2-Difluoro-3-Hydroxy-3-Methylbutanoate
CAS No.	168558-19-8
Molecular Formula	C7H12F2O3
Molecular Weight	182.17 g/mol
Synonyms	Ethyl 2,2-Difluoro-3-hydroxy-3-methylbutyrate; 2,2-Difluoro-3-hydroxy-3-methylbutyric Acid Ethyl Ester; 3-Hydroxy-3-methyl-2,2-difluorobutanoic Acid Ethyl Ester; Ethyl 3-Hydroxy-3-methyl-2,2-difluorobutanoate; Butanoic acid, 2,2-difluoro-3-hydroxy-3-methyl-, ethyl ester; DFHMB Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2,2-Difluoro-3-Hydroxy-3-Methylbutanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee supply reliability and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.