Description

3-o-tert-Butyldimethylsilyl-D-Erythro-Sphingosylphosphorylcholine is a key protected intermediate in the synthesis of complex sphingolipids and their analogs. This compound is critical for researchers and manufacturers requiring high-purity building blocks for lipidomics, drug discovery, and biochemical studies. It is primarily utilized by pharmaceutical R&D teams, fine chemical producers, and academic institutions focused on developing novel therapeutics targeting sphingolipid-mediated pathways.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of sphingosine-1-phosphate (S1P) receptor modulators and other bioactive sphingolipids.
• Biochemical Research: Used in lipidomics research to study cell signaling, apoptosis, and membrane biology.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in lipid analysis.
• Drug Discovery: Enables the creation of novel analogs for screening against targets in oncology, immunology, and neurology.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing specialized, high-value lipid compounds.

Basic Information

Product Name	3-o-tert-Butyldimethylsilyl-D-Erythro-Sphingosylphosphorylcholine
CAS No.	168411-99-2
Molecular Formula	C36H77N2O7PSi
Molecular Weight	709.06 g/mol
Synonyms	3-O-(tert-Butyldimethylsilyl)-D-erythro-sphingosylphosphorylcholine; TBDMS-Sphingosylphosphorylcholine; 3-O-TBDMS-Sphingosylphosphocholine; N-[(2S,3R,4E)-1,3-Dihydroxy-4-octadecen-2-yl]-3-O-[(1,1-dimethylethyl)dimethylsilyl]-2-(trimethylammonio)ethyl phosphate; Sphingosylphosphorylcholine, 3-O-(tert-butyldimethylsilyl)-D-erythro-; Protected Sphingosylphosphorylcholine; Lyso-Sphingomyelin TBDMS ether
EINECS	Contact for details

Quality Control

Our 3-o-tert-Butyldimethylsilyl-D-Erythro-Sphingosylphosphorylcholine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.