Description

Pyridine, 4-Chloro-2-(Chloromethyl)-3-Methyl- is a specialized halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and chloromethyl substituents, makes it a versatile intermediate for constructing complex molecules with high precision. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries, where it is used to introduce specific functional groups and modulate the properties of target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a functionalized pyridine core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the chloromethyl group offers a handle for further derivatization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems and mechanisms.
• Custom Synthesis and Scale-Up: A valuable substrate for contract research organizations (CROs) and CDMOs performing custom synthesis for client projects.

Basic Information

Product Name	Pyridine, 4-Chloro-2-(Chloromethyl)-3-Methyl-
CAS No.	168167-48-4
Molecular Formula	C7H7Cl2N
Molecular Weight	176.04 g/mol
Synonyms	4-Chloro-2-(chloromethyl)-3-methylpyridine; 3-Methyl-4-chloro-2-chloromethylpyridine; 2-(Chloromethyl)-4-chloro-3-methylpyridine; 4-Chloro-3-methyl-2-pyridinemethanol, chloride; 168167-48-4; 4-Chloro-2-chloromethyl-3-methylpyridine
EINECS	Contact for details

Quality Control

Our Pyridine, 4-Chloro-2-(Chloromethyl)-3-Methyl- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.