Description

2-(4-Hydroxypiperidin-1-Yl)Acetic Acid is a versatile piperidine derivative that serves as a crucial building block in advanced organic synthesis. This compound is valued for its bifunctional structure, featuring both a carboxylic acid and a hydroxylated piperidine ring, enabling its use in constructing complex molecular architectures. It is primarily sought by the pharmaceutical and agrochemical industries for the research and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Bioconjugation and Linker Chemistry: The carboxylic acid group facilitates its use as a spacer or linker molecule in bioconjugation and prodrug design.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Fine Chemical Production: An intermediate in the multi-step synthesis of specialty and performance chemicals.

Basic Information

Product Name	2-(4-Hydroxypiperidin-1-Yl)Acetic Acid
CAS No.	168159-33-9
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	1-Carboxymethyl-4-hydroxypiperidine; 4-Hydroxy-1-piperidineacetic Acid; (4-Hydroxy-1-piperidinyl)acetic Acid; 2-(4-Hydroxy-1-piperidinyl)acetic Acid; 1-Piperidineacetic acid, 4-hydroxy-; NSC 339586; 168159-33-9
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of 2-(4-Hydroxypiperidin-1-Yl)Acetic Acid follows current Good Manufacturing Practices (cGMP) where applicable, and each batch is analyzed using advanced techniques like HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.