Description

Cyclopropanecarboxylic Acid, 2-(Acetyloxy)-, Methyl Ester, cis- (9Ci) is a specialized chiral ester derivative of cyclopropanecarboxylic acid, serving as a high-value synthetic intermediate in advanced organic synthesis. Its unique cis-configured cyclopropane ring fused with an acetyloxy functional group makes it a critical building block for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require enantiomerically pure intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane moiety contributes to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex ester-based aroma chemicals.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening reactions and stereoselective transformations.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(Acetyloxy)-, Methyl Ester, cis- (9Ci)
CAS No.	168141-89-7
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	cis-2-(Acetyloxy)cyclopropanecarboxylic acid methyl ester; Methyl cis-2-(acetyloxy)cyclopropanecarboxylate; (1R,2S)-rel-2-(Acetyloxy)cyclopropanecarboxylic Acid Methyl Ester; Methyl (1R,2S)-(-)-2-(Acetoxy)cyclopropanecarboxylate; Acetic acid 2-(methoxycarbonyl)cyclopropyl ester; Cyclopropanecarboxylic acid, 2-(acetyloxy)-, methyl ester, (1R,2S)-rel-; Methyl 2-acetoxycyclopropanecarboxylate (cis-)
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-(Acetyloxy)-, Methyl Ester, cis- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.