Description

Cyclopropanecarboxylic Acid, 2-(Acetyloxy)-, Methyl Ester, trans- (9Ci) is a specialized chiral synthon and ester derivative featuring a cyclopropane ring. This compound matters as a high-value building block in asymmetric synthesis, offering a rigid, strained framework that is crucial for constructing complex molecular architectures with precise stereochemistry. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of proprietary drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and environmental stability.
• Asymmetric Catalysis: Acts as a substrate or ligand precursor in catalytic reactions to study and induce stereoselectivity.
• Material Science Monomer: Investigated for the synthesis of specialized polymers with unique thermal and mechanical properties derived from the strained ring system.
• Flavor & Fragrance Synthesis: Employed as an intermediate for creating complex ester-based aroma molecules.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(Acetyloxy)-, Methyl Ester, trans- (9Ci)
CAS No.	168141-88-6
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	trans-2-(Acetyloxy)cyclopropanecarboxylic acid methyl ester; Methyl trans-2-(acetyloxy)cyclopropanecarboxylate; (1R,2R)-rel-2-(Acetyloxy)cyclopropanecarboxylic Acid Methyl Ester; (1S,2S)-rel-2-(Acetyloxy)cyclopropanecarboxylic Acid Methyl Ester; Methyl (1R,2R)-(-)-2-(Acetoxy)cyclopropanecarboxylate; Methyl (1S,2S)-(+)-2-(Acetoxy)cyclopropanecarboxylate; trans-2-Acetoxycyclopropanecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-(Acetyloxy)-, Methyl Ester, trans- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The product is sensitive to strong alkali and should be kept away from such materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (trans-isomer)
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.