Description

Pyridine, 3-Bromo-5-Isocyanato- (9Ci) is a specialized heterocyclic building block that combines bromo and isocyanato functional groups on a pyridine core. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a precursor for functional polymers, ligands, or metal-organic frameworks (MOFs) due to its dual reactivity.
• Chemical Biology Probes: Employed in the creation of labeled compounds or affinity probes for target identification and binding studies.
• Cross-coupling Reactions: The bromo substituent allows for palladium-catalyzed couplings, while the isocyanate enables urea or carbamate formation.

Basic Information

Product Name	Pyridine, 3-Bromo-5-Isocyanato- (9Ci)
CAS No.	167951-51-1
Molecular Formula	C7H3BrN2O
Molecular Weight	211.02 g/mol
Synonyms	3-Bromo-5-isocyanatopyridine; 5-Bromo-3-isocyanatopyridine; 3-Bromo-5-pyridyl isocyanate; Isocyanic acid, 5-bromo-3-pyridinyl ester; 3-Bromo-5-pyridinyl isocyanate
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 3-Bromo-5-Isocyanato- (9Ci) is produced and tested under a strict quality management system. We ensure high purity and consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.