Description

2-Isocyanatophenyl Methanesulfonate is a specialized aromatic isocyanate derivative, primarily utilized as a key reactive intermediate in advanced organic synthesis. Its value lies in its dual functionality, combining a highly reactive isocyanate group with a methanesulfonate leaving group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its reactive groups allow for the creation of complex, bioactive molecules.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialized polyurethanes and other high-performance polymers with tailored properties.
• Chemical Research & Development: A valuable reagent in medicinal chemistry and process chemistry for constructing complex heterocycles and functionalized aromatic systems.
• Material Science: Employed in the surface modification of materials and the development of novel coatings and adhesives.

Basic Information

Product Name	2-Isocyanatophenyl Methanesulfonate
CAS No.	167951-48-6
Molecular Formula	C9H7NO4S
Molecular Weight	225.22 g/mol
Synonyms	2-Isocyanatophenyl Methanesulfonate; 2-Methanesulfonyloxyphenyl Isocyanate; Methanesulfonic Acid 2-Isocyanatophenyl Ester; o-Isocyanatophenyl Methanesulfonate; 2-(Methylsulfonyloxy)phenyl Isocyanate; (2-Isocyanatophenyl) Methyl Sulfonate; 2-Isocyanatophenol Methanesulfonate Ester; 2-Isocyanatophenyl Methyl Sulfonate
EINECS	Contact for details

Quality Control

Our 2-Isocyanatophenyl Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.