Description

2-Bromo-6-Nitro-Pyridin-3-Ol is a versatile halogenated nitropyridine derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both bromine and nitro substituents on the pyridine ring, makes it a valuable precursor for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Serves as a building block for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme functions.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form complex biaryl structures.
• Nucleophilic Aromatic Substitution: The nitro group activates the pyridine ring for substitution reactions, enabling further functionalization.

Basic Information

Item	Detail
Product Name	2-Bromo-6-Nitro-Pyridin-3-Ol
CAS No.	167683-72-9
Molecular Formula	C5H3BrN2O3
Molecular Weight	218.99 g/mol
Synonyms	3-Hydroxy-2-bromo-6-nitropyridine; 2-Bromo-6-nitro-3-pyridinol; 2-Bromo-6-nitropyridin-3-ol; 6-Nitro-2-bromopyridin-3-ol; 3-Pyridinol, 2-bromo-6-nitro-; 2-Bromo-6-nitro-3-hydroxypyridine; 2-Bromo-6-nitro-3-pyridol
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Nitro-Pyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.