Description

1-Oxa-8-Azaspiro[4.5]Decan-2-One is a versatile spirocyclic heterocyclic compound that serves as a crucial building block in advanced organic synthesis. Its unique molecular architecture, featuring fused oxazolidinone and piperidine rings, makes it a valuable intermediate for constructing complex pharmacophores. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients. Its reliable quality and consistent supply are essential for accelerating drug discovery and process development pipelines.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, leveraging its spirocyclic structure for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Advanced Material Precursor: Potential use in the synthesis of specialized polymers or ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	1-Oxa-8-Azaspiro[4.5]Decan-2-One
CAS No.	167364-29-6
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	8-Aza-1-oxaspiro[4.5]decan-2-one; 1-Oxa-8-azaspiro[4.5]decan-2-one; Oxazaspirodecanone; Spiro[4.5]oxazolidin-2-one derivative; 8-Oxa-1-azaspiro[4.5]decan-2-one (isomer); 167364-29-6; CAS-167364-29-6
EINECS	Contact for details

Quality Control

Our 1-Oxa-8-Azaspiro[4.5]Decan-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.