Description

trans-Benzyl 3-Hydroxycyclopentylcarbamate is a specialized organic compound with a defined stereochemistry, serving as a valuable chiral building block and intermediate in advanced chemical synthesis. Its molecular structure, featuring both a carbamate and a hydroxyl group on a cyclopentane ring, makes it a versatile synthon for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of new therapeutic agents, particularly where precise stereochemical control is critical for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Asymmetric Synthesis: Serves as a building block for constructing complex, enantiomerically pure molecules in process chemistry development.
• Protease Inhibitor Development: Potential intermediate in the development of inhibitors targeting specific enzymes.
• Chemical Biology Probes: Can be incorporated into molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring high-purity chiral intermediates.

Basic Information

Product Name	trans-Benzyl 3-Hydroxycyclopentylcarbamate
CAS No.	167298-57-9
Molecular Formula	C13H17NO3
Molecular Weight	235.28 g/mol
Synonyms	trans-3-Hydroxycyclopentyl benzylcarbamate; Benzyl (1R,3S)-3-hydroxycyclopentylcarbamate (enantiomer); Benzyl (1S,3R)-3-hydroxycyclopentylcarbamate (enantiomer); 3-Hydroxycyclopentanecarbamic acid benzyl ester (trans-); (1R,3S)-rel-3-(Benzyloxycarbonylamino)cyclopentanol; (1S,3R)-rel-3-(Benzyloxycarbonylamino)cyclopentanol; BnOC-3-OH-Cpent; trans-Cyclopentanol-3-carbamate, N-benzyl-
EINECS	Contact for details

Quality Control

Our trans-Benzyl 3-Hydroxycyclopentylcarbamate is manufactured under strict quality control protocols to ensure high chemical purity and stereochemical integrity, suitable for demanding research and development applications. Each batch is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and related substances is provided to guarantee consistency and support regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (trans isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.