Description

1-Boc-4-Cyano-4-(4-Pyridinyl)-Piperidine is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine core with cyano and pyridinyl substituents. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of complex bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel drug candidates, particularly in CNS and oncology therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in route scouting and scale-up synthesis for clinical trial material and commercial manufacturing.
• Protease Inhibitor Synthesis: A crucial building block in the preparation of protease inhibitors and other enzyme-targeted therapeutics.
• Chemical Biology Probes: Utilized in the synthesis of tool compounds and molecular probes for target validation.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical services.

Basic Information

Product Name	1-Boc-4-Cyano-4-(4-Pyridinyl)-Piperidine
CAS No.	167262-92-2
Molecular Formula	C16H21N3O2
Molecular Weight	287.36 g/mol
Synonyms	1-Boc-4-cyano-4-(pyridin-4-yl)piperidine; tert-Butyl 4-cyano-4-(pyridin-4-yl)piperidine-1-carboxylate; 4-Cyano-4-(4-pyridyl)-1-piperidinecarboxylic acid tert-butyl ester; 4-(4-Pyridinyl)-4-cyano-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-cyano-4-(4-pyridyl)piperidine; 4-Cyano-4-(4-pyridinyl)piperidine-1-carboxylic acid tert-butyl ester; BOC-4-Cyano-4-(4-Pyridyl)piperidine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Every batch is characterized and controlled using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) are provided with each shipment, detailing purity, identity, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.