Description

1-Boc-4-Phenyl-4-Piperidinedicarboxylic Acid Methyl Ester is a high-purity, protected piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular scaffolds to construct complex pharmacologically active molecules. It is primarily utilized by the pharmaceutical and biotechnology industries for the development of new therapeutic agents and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system.
• Peptidomimetic Research: Used to incorporate constrained, phenyl-substituted piperidine motifs into peptide analogs to enhance stability and bioavailability.
• Medicinal Chemistry: Serves as a versatile scaffold for constructing libraries of compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Biology: Employed in the development of molecular probes and tool compounds for studying biological pathways and protein interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals for client projects.

Basic Information

Product Name	1-Boc-4-Phenyl-4-Piperidinedicarboxylic Acid Methyl Ester
CAS No.	167262-47-7
Molecular Formula	C19H25NO6
Molecular Weight	363.41 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-4-phenyl-4-piperidinedicarboxylic acid dimethyl ester; 4-Phenyl-1-Boc-piperidine-4,4-dicarboxylic acid dimethyl ester; Dimethyl 1-Boc-4-phenylpiperidine-4,4-dicarboxylate; 1-Boc-4-phenylpiperidine-4,4-dicarboxylic acid dimethyl ester; tert-Butyl 4,4-bis(methoxycarbonyl)-4-phenylpiperidine-1-carboxylate; 1-N-Boc-4-phenyl-4-piperidinedicarboxylic acid dimethyl ester; 4-Phenyl-1-(tert-butoxycarbonyl)piperidine-4,4-dicarboxylic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our production of 1-Boc-4-Phenyl-4-Piperidinedicarboxylic Acid Methyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.