Description

Carbamic Acid, (3-Hydroxy-1,1-Dimethylpropyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized carbamate derivative with a protected hydroxyl group, serving as a versatile synthetic intermediate. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, reliable building blocks for multi-step organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structural motif contributes to biological activity.
• Peptide Mimetics & Prodrug Development: The carbamate and tert-butyl ester groups make it a valuable precursor for creating peptide analogs and prodrug linkers to enhance bioavailability.
• Polymer Chemistry: Serves as a monomer or chain-transfer agent in the synthesis of specialized polyurethanes and functional polymers.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for introducing the (3-hydroxy-1,1-dimethylpropyl)carbamate moiety into target molecules.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Carbamic Acid, (3-Hydroxy-1,1-Dimethylpropyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	167216-22-0
Molecular Formula	C10H21NO3
Molecular Weight	203.28 g/mol
Synonyms	tert-Butyl (3-hydroxy-1,1-dimethylpropyl)carbamate; N-(tert-Butoxycarbonyl)-3-amino-2,2-dimethyl-1-propanol; Boc-AHDMP-OH; (3-Hydroxy-1,1-dimethylpropyl)carbamic acid tert-butyl ester; 1,1-Dimethylethyl N-(3-hydroxy-1,1-dimethylpropyl)carbamate; 2,2-Dimethyl-3-((tert-butoxycarbonyl)amino)-1-propanol; Boc-3-amino-2,2-dimethylpropanol
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, (3-Hydroxy-1,1-Dimethylpropyl)-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports applications requiring high standards, including cGMP manufacturing for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed after each use to minimize exposure to atmospheric moisture and light. For long-term storage, consider using desiccants and storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.