Description

Ethyl n-Cbz-2-Piperidineacetate is a high-purity, protected amino acid ester derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for the controlled introduction of the 2-piperidineacetic acid moiety into complex molecular architectures, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemistry and functional group manipulation.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Peptidomimetic Research: Serves as a crucial building block for constructing peptide analogs and mimetics with enhanced metabolic stability and bioavailability.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and the development of novel small molecule libraries for high-throughput screening.
• Agrochemical Synthesis: Employed in the research and development of advanced pesticides and herbicides that require specific chiral centers for optimal activity.
• Catalyst and Ligand Development: Acts as a precursor for creating novel chiral catalysts and ligands used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract manufacturing organizations (CMOs) producing specialized fine chemicals.

Basic Information

Item	Details
Product Name	Ethyl n-Cbz-2-Piperidineacetate
CAS No.	167170-23-2
Molecular Formula	C₁₇H₂₃NO₄
Molecular Weight	305.37 g/mol
Synonyms	Ethyl 2-[(benzyloxy)carbonyl]amino]-2-piperidineacetate; Ethyl 2-[(Cbz-amino]-2-piperidineacetate; Ethyl N-Carbobenzoxy-2-piperidineacetate; 2-Piperidineacetic acid, N-[(phenylmethoxy)carbonyl]-, ethyl ester; N-Cbz-2-Piperidineacetic Acid Ethyl Ester; (Ethoxycarbonylmethyl)-N-carbobenzoxypiperidine; Ethyl 1-[(benzyloxy)carbonyl]piperidine-2-acetate
EINECS	Contact for details

Quality Control

Our Ethyl n-Cbz-2-Piperidineacetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can support regulatory filings with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.