Description

5-Aminotetramethylrhodamine CAS NO 167095-10-5 is a high-purity, reactive derivative of the classic rhodamine fluorophore, engineered for advanced bioconjugation. This compound is critical for creating stable, bright fluorescent probes and labels with excellent photostability and high quantum yield. It is an essential reagent for researchers and manufacturers in the life sciences, diagnostics, and analytical chemistry sectors who require reliable, high-performance fluorescent tags for sensitive detection and imaging applications.

Application

• Fluorescent Labeling & Probes: Primary application for labeling antibodies, proteins, peptides, and oligonucleotides in fluorescence microscopy (e.g., FISH), flow cytometry, and immunoassays.
• Bioconjugation & Sensor Development: Key building block for synthesizing fluorescent sensors and molecular beacons targeting specific ions, enzymes, or biomolecules due to its reactive amine group.
• Diagnostic Reagents: Used in the formulation of high-sensitivity diagnostic kits for clinical and research purposes, including in vitro diagnostics (IVD).
• Material Science & Nanotechnology: Functionalization of nanoparticles, polymers, and surfaces for bioimaging, tracking, and sensing applications.
• Pharmaceutical Research: Employed in drug discovery for cell-based assays, high-throughput screening (HTS), and studying drug-target interactions via fluorescence.
• Academic & Industrial R&D: A versatile tool across biochemistry, molecular biology, and chemical biology for developing novel analytical methods and detection systems.

Basic Information

Item	Detail
Product Name	5-Aminotetramethylrhodamine
CAS No.	167095-10-5
Molecular Formula	C25H23N3O3
Molecular Weight	413.47 g/mol
Synonyms	5-Amino TAMRA; 5-TAMRA amine; 5-Carboxytetramethylrhodamine amine; 6-Amino-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one; 5-Amino-3',6'-bis(dimethylamino)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one; TAMRA-5-amine; Reactive TAMRA derivative; Rhodamine derivative, amine-functionalized
EINECS	Contact for details

Quality Control

Our 5-Aminotetramethylrhodamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification, and functional validation for labeling efficiency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee the material meets the stringent requirements for research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is light-sensitive; prolonged exposure to light should be avoided to prevent degradation. Keep the container sealed in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	Dark red to purple powder
Identification (HPLC/UV-Vis)	Conforms
Purity (HPLC)	≥ 95%
Absorption Maximum (λmax)	~540-560 nm
Emission Maximum	~565-585 nm
Extinction Coefficient	Contact for details
Solubility	Soluble in DMSO, DMF, methanol
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.