Description

2-Azabicyclo[2.2.1]Heptane-2-Carboxylic Acid, 3-Oxo-, 1,1-Dimethylethyl Ester is a high-value, advanced pharmaceutical intermediate characterized by its unique bridged bicyclic structure. This compound is essential for the synthesis of complex molecules, offering a critical chiral scaffold for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs), particularly in the areas of neurology and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Asymmetric Synthesis: Used in the development of enantioselective synthetic routes due to its rigid, three-dimensional structure.
• Protease Inhibitor Development: Potential precursor in the synthesis of inhibitors targeting specific enzymatic pathways.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized chemical entities.
• Academic & Industrial R&D: A valuable reagent for exploratory chemistry in both university laboratories and industrial R&D centers.

Basic Information

Product Name	2-Azabicyclo[2.2.1]Heptane-2-Carboxylic Acid, 3-Oxo-, 1,1-Dimethylethyl Ester
CAS No.	167081-32-5
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	tert-Butyl 3-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylate; (1R,4S)-1,7,7-Trimethyl-3-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylic Acid tert-Butyl Ester; 2-tert-Butoxycarbonyl-2-azabicyclo[2.2.1]heptan-3-one; 2-Boc-2-azabicyclo[2.2.1]heptan-3-one; Boc-ABH; 3-Oxo-2-azabicyclo[2.2.1]heptane-2-carboxylic acid 1,1-dimethylethyl ester; N-Boc-3-oxo-2-azabicyclo[2.2.1]heptane
EINECS	Contact for details

Quality Control

Our production of 2-Azabicyclo[2.2.1]Heptane-2-Carboxylic Acid, 3-Oxo-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.