Description

Methyl 3-(3-Aminophenyl)-2-([(tert-Butoxy)Carbonyl]Amino)Propanoate is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical key building block in the development of complex pharmaceutical intermediates and bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for peptide synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid ester building block.
• Protease Inhibitor Research: Serves as a key scaffold in the development of enzyme inhibitors for therapeutic applications.
• Agrochemical Development: Employed in the research and synthesis of advanced crop protection agents and herbicides.
• Chemical Biology Probes: Utilized for creating labeled compounds and probes for studying biological pathways and mechanisms.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific chiral and functionalized intermediates.

Basic Information

Item	Details
Product Name	Methyl 3-(3-Aminophenyl)-2-([(tert-Butoxy)Carbonyl]Amino)Propanoate
CAS No.	166888-37-5
Molecular Formula	C15H22N2O4
Molecular Weight	294.35 g/mol
Synonyms	Boc-3-Amino-L-phenylalanine methyl ester; Methyl (2S)-3-(3-aminophenyl)-2-[(tert-butoxycarbonyl)amino]propanoate; (S)-Methyl 3-(3-aminophenyl)-2-((tert-butoxycarbonyl)amino)propanoate; Boc-L-3-Amino-Phe-OMe; N-Boc-3-amino-L-phenylalanine methyl ester; 3-Amino-N-Boc-L-phenylalanine methyl ester; Boc-3-Amino-Phe-OMe
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(3-Aminophenyl)-2-([(tert-Butoxy)Carbonyl]Amino)Propanoate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.