Description

4-(3-Isocyanatobenzyl)Morpholine is a specialized aromatic isocyanate derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its unique bifunctional reactivity, combining the isocyanate group for urethane/urea formation with the morpholine moiety, which can impart desirable solubility and pharmacological properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of high-performance polymers and specialty adhesives seeking to modify material properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the morpholine ring can enhance systemic activity.
• Polymer Modification: Acts as a reactive monomer or cross-linking agent in polyurethane and polyurea systems to tailor flexibility, adhesion, and chemical resistance.
• Specialty Coatings & Adhesives: Incorporated into formulations to improve durability, weatherability, and bonding strength in high-performance applications.
• Chemical Research: Serves as a versatile reagent in academic and industrial R&D for exploring new heterocyclic compounds and material science applications.
• Liquid Crystal & Electronic Materials: Potential precursor in the synthesis of advanced organic materials for display and semiconductor technologies.

Basic Information

Product Name	4-(3-Isocyanatobenzyl)Morpholine
CAS No.	166740-66-5
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	3-((Morpholin-4-yl)methyl)phenyl isocyanate; 1-Isocyanato-3-(morpholin-4-ylmethyl)benzene; 4-(3-Isocyanatobenzyl)morpholine; m-Isocyanatobenzylmorpholine; 3-(Morpholinomethyl)phenyl isocyanate; Benzene, 1-isocyanato-3-[(4-morpholinyl)methyl]-
EINECS	Contact for details

Quality Control

Our 4-(3-Isocyanatobenzyl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets precise specifications for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and compliance assurance for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C to minimize volatility and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	~1.18 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.