Description

1H-Indene-1-Carboxylicacid,1-Amino-2,3-Dihydro-,Methylester,(S)-(9Ci) CAS NO 166735-16-6 is a high-purity, single-enantiomer chiral building block of significant interest in advanced organic synthesis. Its value lies in its unique indene-fused structure bearing both amino and ester functionalities, making it a versatile precursor for constructing complex, optically active molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic and R&D: A valuable tool for methodological studies in organic chemistry, particularly in reactions exploring new C-N and C-C bond formations.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors and advanced polymeric materials with specific optical properties.

Basic Information

Product Name	1H-Indene-1-Carboxylicacid,1-Amino-2,3-Dihydro-,Methylester,(S)-(9Ci)
CAS No.	166735-16-6
Molecular Formula	C11H11NO2
Molecular Weight	189.21 g/mol
Synonyms	(S)-1-Amino-2,3-dihydro-1H-indene-1-carboxylic acid methyl ester; Methyl (1S)-1-amino-2,3-dihydro-1H-indene-1-carboxylate; (S)-1-Aminoindane-1-carboxylic acid methyl ester; (1S)-1-Amino-2,3-dihydro-1H-indene-1-carboxylic Acid Methyl Ester; (S)-AIDA methyl ester; 1H-Indene-1-carboxylic acid, 1-amino-2,3-dihydro-, methyl ester, (S)-; (S)-1-(Methoxycarbonyl)-1-aminoindane
EINECS	Contact for details

Quality Control

Our 1H-Indene-1-Carboxylicacid,1-Amino-2,3-Dihydro-,Methylester,(S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.