Description

1-Chloro-2-(2-Chloro-Ethyl)-3-Methyl-Benzo[4,5]Imidazo[1,2-A]Pyridine-4-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop next-generation drug candidates targeting complex diseases.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex benzoimidazopyridine cores, enabling structure-activity relationship (SAR) studies.
• Agrochemical Research: Potential application as an intermediate in developing new agrochemicals with specific biological activity due to its halogenated heterocyclic structure.
• Material Science Precursor: Investigated for use in synthesizing organic electronic materials and ligands for catalytic systems.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and contract manufacturers engaged in custom synthesis and process development for clients.

Basic Information

Product Name	1-Chloro-2-(2-Chloro-Ethyl)-3-Methyl-Benzo[4,5]Imidazo[1,2-A]Pyridine-4-Carbonitrile
CAS No.	166671-24-5
Molecular Formula	C₁₅H₁₁Cl₂N₃
Molecular Weight	304.17 g/mol
Synonyms	1-Chloro-2-(2-chloroethyl)-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile; 4-Cyano-1-chloro-2-(2-chloroethyl)-3-methylbenzo[4,5]imidazo[1,2-a]pyridine; Benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile, 1-chloro-2-(2-chloroethyl)-3-methyl-; 166671-24-5; 1-Chloro-2-(2-chloroethyl)-3-methyl-1H-benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 1-Chloro-2-(2-Chloro-Ethyl)-3-Methyl-Benzo[4,5]Imidazo[1,2-A]Pyridine-4-Carbonitrile adheres to stringent quality protocols suitable for pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure consistent quality and traceability. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. Our quality management system supports compliance with cGMP and ICH guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the complex heterocyclic structure, prolonged exposure to high humidity or extreme temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.