Description

2-Isocyano-Pent-4-Enoic Acid Ethyl Ester is a versatile and highly reactive organic building block, primarily valued for its dual functional groups—the isocyano and the α,β-unsaturated ester—which enable diverse cycloaddition and multicomponent reactions. This compound is essential for the efficient synthesis of complex heterocyclic scaffolds, including pyrroles and other nitrogen-containing pharmacophores. It is a critical intermediate for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel heterocyclic compounds with potential biological activity.
• Agrochemical Research: Used in creating new active ingredients for crop protection products.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Academic & Process Chemistry: Enables multicomponent reactions (MCRs) like the Passerini and Ugi reactions for rapid library synthesis in drug discovery.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex organic molecules for various industrial applications.

Basic Information

Product Name	2-Isocyano-Pent-4-Enoic Acid Ethyl Ester
CAS No.	166655-28-3
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	Ethyl 2-Isocyanopent-4-enoate; 4-Pentenoic acid, 2-isocyano-, ethyl ester; 2-Isocyanopent-4-enoic Acid Ethyl Ester; Ethyl 2-Isocyano-4-pentenoate; (Ethoxycarbonyl)but-3-enyl isocyanide
EINECS	Contact for details

Quality Control

Our 2-Isocyano-Pent-4-Enoic Acid Ethyl Ester is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation due to its highly volatile and easily oxidized nature. Keep away from heat, sparks, and open flame. The container should be stored in a cool, well-ventilated area separate from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.