Description

6-[Bromoacetamido]Tetramethylrhodamine is a reactive, fluorescent dye derivative widely used as a critical labeling reagent in advanced biochemical research. Its core value lies in its ability to form stable covalent bonds with thiol groups, enabling the specific tagging and visualization of biomolecules. This compound is essential for researchers and manufacturers in the fields of bioconjugation, fluorescence microscopy, and flow cytometry, where precise and bright labeling is required.

Application

• Bioconjugation and Protein Labeling: Covalently attaches to cysteine residues in proteins and peptides for fluorescence tagging.
• Fluorescence Microscopy: Used as a bright, photostable probe for cellular and tissue imaging.
• Flow Cytometry: Serves as a fluorescent marker for cell surface or intracellular antigen detection.
• Nucleic Acid Labeling: Can be conjugated to modified oligonucleotides for FISH (Fluorescence In Situ Hybridization) applications.
• Antibody-Dye Conjugate Production: A key intermediate in the manufacturing of fluorescent antibody conjugates for diagnostics and research.
• Sensor Development: Incorporated into chemical sensors and probes for detecting specific analytes.

Basic Information

Item	Details
Product Name	6-[Bromoacetamido]Tetramethylrhodamine
CAS No.	166442-39-3
Molecular Formula	C29H28BrN3O5
Molecular Weight	578.46 g/mol
Synonyms	6-Bromoacetamido TAMRA; 6-BAT; 6-TAMRA Bromoacetamide; 6-Carboxytetramethylrhodamine Bromoacetamide; TAMRA-6-Bromoacetamide; 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester bromoacetamide derivative; Reactive TAMRA dye; Bromoacetyl TAMRA
EINECS	Contact for details

Quality Control

Our 6-[Bromoacetamido]Tetramethylrhodamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and absorbance/fluorescence spectroscopy to ensure performance consistency. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee the material meets the high standards required for sensitive life science applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Dark red to purple solid
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 95.0%
Absorption Max (λmax)	550 - 555 nm
Emission Max	575 - 585 nm
Solubility	Soluble in DMF, DMSO, acetonitrile
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.