Description

2-(1,4-Dioxaspiro[4.5]Decan-8-Yl)-1,2,3,4-Tetrahydroisoquinoline is a specialized heterocyclic organic compound featuring a tetrahydroisoquinoline scaffold fused with a spirocyclic ketal moiety. This unique molecular architecture makes it a valuable synthetic intermediate and building block in advanced organic synthesis, particularly for constructing complex nitrogen-containing frameworks. It is primarily needed by pharmaceutical research and fine chemical synthesis laboratories engaged in the development of novel active pharmaceutical ingredients (APIs) and other high-value chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological or cardiovascular pathways.
• Organic Synthesis Building Block: Used to construct complex polycyclic and spirocyclic compounds in medicinal chemistry and materials science research.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel chiral ligands or organocatalysts for asymmetric synthesis.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, or plant growth regulators with novel modes of action.
• Academic and R&D Laboratories: Used in fundamental chemical research to explore new synthetic methodologies and reaction mechanisms.
• Fine Chemical Production: Incorporated into the manufacture of specialty chemicals, dyes, or advanced materials requiring specific heterocyclic structures.

Basic Information

Product Name	2-(1,4-Dioxaspiro[4.5]Decan-8-Yl)-1,2,3,4-Tetrahydroisoquinoline
CAS No.	166398-22-7
Molecular Formula	C19H25NO2
Molecular Weight	299.41 g/mol
Synonyms	2-(1,4-Dioxaspiro[4.5]decan-8-yl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-2-(1,4-dioxaspiro[4.5]decan-8-yl)isoquinoline; 8-(1,2,3,4-Tetrahydroisoquinolin-2-yl)-1,4-dioxaspiro[4.5]decane; Spiro[1,3-dioxolane-2,1'-cyclohexane]-8-yl tetrahydroisoquinoline derivative. Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-(1,4-Dioxaspiro[4.5]Decan-8-Yl)-1,2,3,4-Tetrahydroisoquinoline is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity (typically by HPLC or GC), identity confirmation (by IR, NMR), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Research Grade)
Purity (GC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.