Description

5-Bromobenzofuran-2(3H)-One is a high-purity brominated benzofuranone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated heterocyclic structure makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection agent synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging its halogenated heterocyclic core.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and organic electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and ring-forming transformations to create diverse chemical libraries for screening.
• Academic & Contract Research: Essential reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-Bromobenzofuran-2(3H)-One
CAS No.	166386-69-2
Molecular Formula	C8H5BrO2
Molecular Weight	213.03 g/mol
Synonyms	5-Bromo-2(3H)-benzofuranone; 5-Bromo-2-benzofuran-1(3H)-one; 5-Bromophthalide; 5-Bromo-1(3H)-isobenzofuranone; 5-Bromo-3H-isobenzofuran-1-one; 5-Bromoisobenzofuran-1(3H)-one; 5-Bromo-1-oxo-1,3-dihydroisobenzofuran
EINECS	Contact for details

Quality Control

Our 5-Bromobenzofuran-2(3H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity while monitoring for specified impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.