Description

4-Chloro-3-Hydroxy-Benzoic Acid Methyl Ester is a versatile aromatic ester building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a phenolic hydroxyl and an ester group ortho to a chloro substituent, makes it a valuable precursor for constructing complex molecules. This compound is primarily utilized by research institutions and industrial R&D departments engaged in pharmaceutical, agrochemical, and specialty chemical development.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those with halogenated aromatic backbones.
• Agrochemical Synthesis: Used in the research and development of herbicides, fungicides, and other crop protection agents.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed coupling reactions.
• Polymer Chemistry: Can be incorporated as a monomer or functional modifier to impart specific properties into polymer chains.
• Dye and Pigment Intermediate: Employed in the synthesis of complex organic dyes and colorants.
• Chemical Research: A valuable reagent for methodological studies in organic chemistry, including esterification, etherification, and cross-coupling reactions.

Basic Information

Product Name	4-Chloro-3-Hydroxy-Benzoic Acid Methyl Ester
CAS No.	166272-81-7
Molecular Formula	C8H7ClO3
Molecular Weight	186.59 g/mol
Synonyms	Methyl 4-Chloro-3-hydroxybenzoate; 3-Hydroxy-4-chlorobenzoic Acid Methyl Ester; Benzoic acid, 4-chloro-3-hydroxy-, methyl ester; Methyl 3-hydroxy-4-chlorobenzoate; 4-Chloro-3-hydroxy methyl benzoate
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Hydroxy-Benzoic Acid Methyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.