Description

(R)-Methyl 2-((S)-2,2-Dimethyl-1,3-Dioxolan-4-Yl)-2-(Tosyloxy)Acetate (Wxg00543) is a high-value chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its core value lies in its well-defined stereochemistry, which is critical for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs), chiral ligands, and other specialty chemicals where stereochemical purity is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, especially in the development of antiviral, anticancer, and neurological disorder treatments.
• Asymmetric Synthesis: Used in the construction of chiral centers for the production of enantiomerically pure compounds via nucleophilic substitution or further functional group transformations.
• Fine Chemical Production: Serves as a precursor for the manufacture of advanced materials, specialty polymers, and high-performance liquid crystals.
• Catalyst and Ligand Development: Employed in the research and synthesis of novel chiral catalysts and ligands for catalytic asymmetric reactions.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry, enabling research into new synthetic pathways and stereoselective processes.

Basic Information

Product Name	(R)-Methyl 2-((S)-2,2-Dimethyl-1,3-Dioxolan-4-Yl)-2-(Tosyloxy)Acetate (Wxg00543)
CAS No.	166249-17-8
Molecular Formula	C15H20O7S
Molecular Weight	344.38 g/mol
Synonyms	Methyl (2R)-2-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4-methylphenyl)sulfonyloxy]acetate; (R)-Methyl 2-((S)-2,2-Dimethyl-1,3-dioxolan-4-yl)-2-(p-toluenesulfonyloxy)acetate; (4S)-2,2-Dimethyl-4-[(1R)-1-methoxycarbonyl-2-(tosyloxy)ethyl]-1,3-dioxolane; (R)-Methyl 2-(Tosyloxy)-2-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)acetate; Wxg00543; Chiral tosylate ester intermediate; p-Toluenesulfonic acid 2-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-((R)-methoxycarbonyl)ethyl ester
EINECS	Contact for details

Quality Control

Our (R)-Methyl 2-((S)-2,2-Dimethyl-1,3-Dioxolan-4-Yl)-2-(Tosyloxy)Acetate is manufactured under strict quality control protocols to ensure high chemical and stereochemical purity, which is critical for sensitive synthetic applications. Each batch is analyzed using advanced chromatographic (HPLC, GC) and spectroscopic (NMR) techniques to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.