Description

1-(2-Chloropyridin-3-Yl)-3-(Dimethylamino)Prop-2-En-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique enone structure. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Employed in organic synthesis for the construction of complex nitrogen-containing heterocycles.
• Process Development: Used in scale-up and route scouting for the commercial manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-(2-Chloropyridin-3-Yl)-3-(Dimethylamino)Prop-2-En-1-One
CAS No.	166196-84-5
Molecular Formula	C10H11ClN2O
Molecular Weight	210.66 g/mol
Synonyms	3-(Dimethylamino)-1-(2-chloro-3-pyridinyl)-2-propen-1-one; 1-(2-Chloro-3-pyridinyl)-3-(dimethylamino)-2-propen-1-one; 2-Chloro-3-(3-(dimethylamino)acryloyl)pyridine; (E)-1-(2-Chloropyridin-3-yl)-3-(dimethylamino)prop-2-en-1-one; 166196-84-5; 3-(Dimethylamino)-1-(2-chloropyridin-3-yl)prop-2-en-1-one; Propenone, 1-(2-chloro-3-pyridinyl)-3-(dimethylamino)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.