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4-(4-Bromo-1H-Pyrazol-3-Yl)Pyridine CAS NO 166196-54-9


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CAS No.:166196-54-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-(4-Bromo-1H-Pyrazol-3-Yl)Pyridine is a high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
  • Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with specific modes of action.
  • Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and other optoelectronic devices.
  • Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
  • Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
  • Library Synthesis: A versatile scaffold for generating diverse compound libraries in high-throughput screening and drug discovery campaigns.

Basic Information

Product Name 4-(4-Bromo-1H-Pyrazol-3-Yl)Pyridine
CAS No. 166196-54-9
Molecular Formula C8H6BrN3
Molecular Weight 224.06 g/mol
Synonyms 4-(4-Bromo-1H-pyrazol-3-yl)pyridine; 3-(4-Pyridinyl)-4-bromo-1H-pyrazole; 4-Bromo-3-(4-pyridinyl)-1H-pyrazole; 4-(4-Bromo-1H-pyrazol-3-yl)pyridine; Pyridine, 4-(4-bromo-1H-pyrazol-3-yl)-; 166196-54-9
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Quality Control

Our 4-(4-Bromo-1H-Pyrazol-3-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive material from humidity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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