Description

tert-Butyl (3R)-3-Amino-5-Methylhexanoate, 97 is a high-purity chiral building block of significant importance in modern organic synthesis. This compound serves as a critical intermediate for the production of complex, biologically active molecules, enabling precise stereochemical control. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly for cardiovascular and central nervous system (CNS) targeted therapies.
• Peptide Mimetics: Used in the construction of peptidomimetics and modified amino acid derivatives for medicinal chemistry research.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Agrochemical Research: Serves as a building block for developing novel, chiral active ingredients with specific biological activity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis: A valuable substrate for contract research organizations (CROs) and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	tert-Butyl (3R)-3-Amino-5-Methylhexanoate, 97
CAS No.	166023-29-6
Molecular Formula	C₁₁H₂₃NO₂
Molecular Weight	201.31 g/mol
Synonyms	(R)-tert-Butyl 3-amino-5-methylhexanoate; (3R)-3-Amino-5-methylhexanoic acid tert-butyl ester; tert-Butyl (R)-3-amino-5-methylhexanoate; (R)-3-Amino-5-methylhexanoic acid tert-butyl ester; (R)-3-(tert-Butoxycarbonylamino)-5-methylhexanoic acid (protected form precursor); (3R)-3-Amino-5-methyl-hexanoic acid 1,1-dimethylethyl ester; BOC-(R)-3-Amino-5-methylhexanoic acid tert-butyl ester (common misnomer); (R)-5-Methyl-3-aminocaproic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (3R)-3-Amino-5-Methylhexanoate, 97 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the specified 97% minimum purity and consistent stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.