Description

3-Trimethylsilyl-1-propylboronic acid pinacol ester is a high-purity, organosilicon-protected boronic ester building block essential for modern synthetic chemistry. This compound is valued for its enhanced stability and reactivity in cross-coupling reactions, particularly Suzuki-Miyaura couplings, enabling the efficient construction of complex molecular architectures. It is a critical reagent for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise and reliable synthesis is paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring the introduction of specific alkylsilane-functionalized groups.
• Material Science & OLED Development: Serves as a precursor for creating organic semiconductors, liquid crystals, and light-emitting materials for electronic displays.
• Organic Synthesis & Methodology: A versatile reagent in academic and industrial R&D for constructing carbon-carbon bonds and exploring new catalytic cycles.
• Peptide Modification & Bioconjugation: Facilitates the site-specific labeling and functionalization of biomolecules for diagnostic and therapeutic applications.
• Polymer Chemistry: Employed to synthesize functionalized monomers for specialty polymers with tailored properties.

Basic Information

Product Name	3-Trimethylsilyl-1-propylboronic acid pinacol ester
CAS No.	165904-32-5
Molecular Formula	C₁₂H₂₇BO₂Si
Molecular Weight	242.24 g/mol
Synonyms	3-(Trimethylsilyl)propylboronic acid pinacol ester; (3-(Trimethylsilyl)propyl)boronic acid pinacol ester; 1-Trimethylsilyl-3-propaneboronic acid pinacol ester; 3-Trimethylsilylpropylboronic acid pinacol ester; Pinacol (3-(trimethylsilyl)propyl)boronate; (3-(Trimethylsilyl)propyl)boronic acid, cyclic ester with pinacol; TMS-propyl-Bpin
EINECS	Contact for details

Quality Control

Every batch of our 3-Trimethylsilyl-1-propylboronic acid pinacol ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by NMR/GC), identity, and impurity profiles. Our quality commitment supports applications requiring reliable and reproducible performance in sensitive synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC / NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.