Description

1-Piperidinecarboxylic Acid, 2-(Hydroxymethyl)-, Methyl Ester is a versatile piperidine derivative and a key chiral building block in organic synthesis. This compound matters for its role as a crucial intermediate in the development of complex pharmaceutical molecules and fine chemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Employed in medicinal chemistry for constructing peptide analogs and conformationally restricted scaffolds.
• Fine Chemical Production: Utilized in custom synthesis and the manufacture of high-value specialty chemicals for various industrial applications.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and novel synthetic route exploration.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 2-(Hydroxymethyl)-, Methyl Ester
CAS No.	165104-66-5
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	Methyl 2-(hydroxymethyl)piperidine-1-carboxylate; (2-Hydroxymethyl-piperidin-1-yl)-carboxylic acid methyl ester; 1-Carbomethoxy-2-(hydroxymethyl)piperidine; 2-(Hydroxymethyl)-1-piperidinecarboxylic acid methyl ester; Methyl 1-piperidinecarboxylate, 2-(hydroxymethyl)-; 1-Piperidinecarboxylic acid, 2-(hydroxymethyl)-, methyl ester; 2-Piperidinemethanol, 1-(methoxycarbonyl)-; Methyl (2-hydroxymethyl)piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylic Acid, 2-(Hydroxymethyl)-, Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (Typical)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.