Description

Methyl 4-(tert-Butoxycarbonylamino)Benzoate CAS NO 164596-20-7 is a protected amino acid derivative, specifically a methyl ester of a Boc-protected para-aminobenzoic acid. This compound is a crucial building block in organic synthesis, valued for its role in introducing the Boc-protected aniline moiety into target molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug molecules, particularly those containing aniline or benzamide pharmacophores.
• Peptide Mimetics & Conjugate Chemistry: Used in the preparation of non-natural amino acids and for coupling reactions to create peptide-drug conjugates or labeled compounds.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic semiconductors.
• Chemical Biology Probes: Utilized to create tagged or protected aniline derivatives for studying biological pathways and protein interactions.
• Custom Synthesis & Scale-Up: A reliable starting material for contract research organizations (CROs) and CDMOs for custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	Methyl 4-(tert-Butoxycarbonylamino)Benzoate
CAS No.	164596-20-7
Molecular Formula	C13H17NO4
Molecular Weight	251.28 g/mol
Synonyms	Methyl 4-[(tert-butoxycarbonyl)amino]benzoate; Methyl p-(N-Boc-amino)benzoate; 4-(Boc-amino)benzoic acid methyl ester; Benzoic acid, 4-[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester; Boc-4-aminobenzoic acid methyl ester; Methyl N-Boc-4-aminobenzoate; p-(N-Boc)aminobenzoic acid methyl ester; N-Boc-4-aminobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-(tert-Butoxycarbonylamino)Benzoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.