Description

(R)-Methyl Nipecotate CAS NO 164323-85-7 is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its role as a key precursor for the synthesis of complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and other therapeutics.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for efficacy.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral catalysts and ligands used in asymmetric synthesis to induce high enantioselectivity.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals and flavors & fragrances requiring specific stereochemistry.
• Academic and R&D: A valuable reagent for medicinal chemistry research, process development, and exploring new synthetic methodologies in university and corporate laboratories.

Basic Information

Product Name	(R)-Methyl Nipecotate
CAS No.	164323-85-7
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(R)-Methyl piperidine-3-carboxylate; (R)-Methyl 3-piperidinecarboxylate; Methyl (R)-nipecotate; (R)-Nipecotic acid methyl ester; (3R)-Piperidine-3-carboxylic acid methyl ester; (R)-1,2,3,6-Tetrahydropyridine-3-carboxylic acid methyl ester; (R)-3-Carbomethoxypiperidine
EINECS	Contact for details

Quality Control

Our (R)-Methyl Nipecotate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, NMR, and GC/MS, to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.