Description

1-tert-Butyl 2-Methyl 1,2,3,6-Tetrahydropyridine-1,2-Dicarboxylate is a high-purity, protected dipeptide-like building block of significant interest in advanced organic synthesis. This compound is valued for its role as a versatile synthetic intermediate, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those containing piperidine or tetrahydropyridine scaffolds.
• Peptidomimetic Research: Used in the design and synthesis of peptidomimetics, where it serves as a constrained, non-natural amino acid analog to modulate biological activity and stability.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore new chemical entities for various therapeutic targets.
• Chemical Biology: Acts as a building block for creating specialized probes and tool compounds to study biological pathways.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of client-specified target molecules.
• Academic Research: Serves as a starting material in methodological development and novel reaction exploration within university and institutional laboratories.

Basic Information

Product Name	1-tert-Butyl 2-Methyl 1,2,3,6-Tetrahydropyridine-1,2-Dicarboxylate
CAS No.	164298-41-3
Molecular Formula	C12H19NO4
Molecular Weight	241.28 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-2-(methoxycarbonyl)-1,2,3,6-tetrahydropyridine; 1-Boc-2-(COOMe)-1,2,3,6-tetrahydropyridine; tert-Butyl methyl 1,2,3,6-tetrahydropyridine-1,2-dicarboxylate; Methyl 1-(tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridine-2-carboxylate; 1,2,3,6-Tetrahydropyridine-1,2-dicarboxylic acid 1-tert-butyl 2-methyl ester; Boc-1,2,3,6-tetrahydropyridine-2-COOMe; 1-N-Boc-2-methoxycarbonyl-1,2,3,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 2-Methyl 1,2,3,6-Tetrahydropyridine-1,2-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.