Description

Carbamic Acid, [(Trimethylsilyl)Oxy]-, 1,1-Dimethylethyl Ester (9Ci) CAS NO 164169-42-0 is a specialized organosilicon-protected carbamate derivative, serving as a versatile building block and protective reagent in advanced organic synthesis. Its core value lies in providing a robust, silyl-protected carbamate group that is stable under a wide range of reaction conditions yet can be selectively deprotected, enabling complex multi-step syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protected amine functionalities.
• Peptide Synthesis: Used as a protective group for amines during solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Agrochemical Development: Intermediate in the production of advanced herbicides, fungicides, and insecticides that require carbamate or urea motifs.
• Organic Synthesis Reagent: Employed as a versatile reagent for the protection of primary and secondary amines in complex multi-step synthetic routes.
• Material Science Research: Precursor for creating functionalized polymers and dendrimers with specific surface properties.
• Chemical Biology Probes: Used in the development of probes and linkers for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	Carbamic Acid, [(Trimethylsilyl)Oxy]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	164169-42-0
Molecular Formula	C8H19NO2Si
Molecular Weight	189.33 g/mol
Synonyms	tert-Butyl (trimethylsilyloxy)carbamate; N-(tert-Butoxycarbonyloxy)trimethylsilane; BOC-ON (Trimethylsilyl) Ester; tert-Butyl N-(trimethylsilyloxy)carbamate; (tert-Butoxycarbonyloxy)trimethylsilane; 1,1-Dimethylethyl [(trimethylsilyl)oxy]carbamate; BOC-oxy-trimethylsilane; TMS-BOC
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(Trimethylsilyl)Oxy]-, 1,1-Dimethylethyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and light-sensitive nature, store the product in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) for long-term stability. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.