Description

(2,5-Dioxopyrrolidin-1-yl) 4-[chloro(diphenyl)methyl]benzoate is a specialized chemical intermediate featuring a reactive N-hydroxysuccinimide (NHS) ester group and a sterically hindered chlorodiphenylmethyl moiety. This compound matters for its utility in advanced organic synthesis, particularly in the formation of stable amide bonds under mild conditions, which is critical for constructing complex molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications such as peptide coupling, bioconjugation, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs.
• Peptide Synthesis: Used as an efficient coupling agent for forming amide bonds in solid-phase and solution-phase peptide synthesis.
• Bioconjugation: Facilitates the labeling and modification of proteins, antibodies, and other biomolecules for diagnostic and therapeutic research.
• Agrochemical Research: Serves as an intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the surface functionalization of polymers and nanoparticles to introduce specific chemical properties.
• Cross-linking Agent: Acts as a reagent to create covalent cross-links between molecules in polymer chemistry and hydrogel formation.

Basic Information

Product Name	(2,5-Dioxopyrrolidin-1-yl) 4-[chloro(diphenyl)methyl]benzoate
CAS No.	164168-40-5
Molecular Formula	C24H18ClNO4
Molecular Weight	419.86 g/mol
Synonyms	4-(Chlorodiphenylmethyl)benzoic acid N-hydroxysuccinimide ester; 4-[Chloro(diphenyl)methyl]benzoic acid 2,5-dioxo-1-pyrrolidinyl ester; 4-(α-Chloro-α-phenylbenzyl)benzoyloxysuccinimide; NHS ester of 4-(chlorotrityl)benzoic acid; 4-(Cl-Trityl)benzoic acid NHS ester; 4-(Chlorotriphenylmethyl)benzoic acid N-succinimidyl ester; 1-{[4-(Chlorodiphenylmethyl)benzoyl]oxy}-2,5-pyrrolidinedione
EINECS	Contact for details

Quality Control

Our (2,5-Dioxopyrrolidin-1-yl) 4-[chloro(diphenyl)methyl]benzoate undergoes rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing specific results from HPLC, NMR, and other relevant analytical methods are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.