Description

Asoprisnil Ecamate is a synthetic, steroidal selective progesterone receptor modulator (SPRM) of significant pharmaceutical interest. Its primary value lies in its targeted mechanism of action, which allows for the development of novel therapeutic agents for hormone-dependent conditions. This compound is essential for research institutions and pharmaceutical companies engaged in the development of treatments for gynecological disorders and as a key intermediate in advanced drug synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced steroidal active pharmaceutical ingredients (APIs).
• Biomedical Research: Used as a reference standard and probe compound in preclinical studies to investigate progesterone receptor biology and signaling pathways.
• Drug Discovery & Development: A key candidate for developing new therapeutic agents targeting endometriosis, uterine fibroids (leiomyomas), and other hormone-responsive conditions.
• Clinical Research Material: Employed in the formulation development and stability testing for potential SPRM-based medications.
• Academic Research: Utilized in university and institutional labs for studying the structure-activity relationships (SAR) of selective receptor modulators.

Basic Information

Product Name	Asoprisnil Ecamate
CAS No.	163883-88-3
Molecular Formula	C29H35NO4
Molecular Weight	461.60 g/mol
Synonyms	Asoprisnil Ecamate; J867; 11β-[4-(Dimethylamino)phenyl]-17α-hydroxy-21-methoxy-19-norpregna-4,9-diene-3,20-dione 17-acetate; (11β,17α)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-21-methoxy-19-norpregna-4,9-diene-3,20-dione acetate; J 867; Asoprisnil Ecomate; Asoprisnil Ester
EINECS	Contact for details

Quality Control

Every batch of Asoprisnil Ecamate is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.