Description

D-Galactitol, 2-Deoxy-2-(1,1-Dimethylethoxy)Carbonylamino-5,6-o-(1-Methylethylidene)-3-o-(Phenylmethyl)-1-o-(Triphenylmethyl)-, 4-Acetate CAS NO 163707-60-6 is a sophisticated, multi-protected carbohydrate derivative, specifically engineered as a critical chiral building block for advanced organic synthesis. Its complex structure, featuring orthogonal protecting groups (trityl, benzyl, isopropylidene, acetate, and Boc), provides exceptional control over regioselective reactions, making it indispensable for constructing complex bioactive molecules. This high-purity intermediate is primarily targeted at pharmaceutical R&D and fine chemical sectors for the development of novel therapeutics, including antibiotics, antiviral agents, and glycosidase inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex active pharmaceutical ingredients (APIs), particularly in carbohydrate-based drug discovery.
• Glycochemistry Research: Used in academic and industrial laboratories for studying glycosylation reactions and synthesizing oligosaccharides or glycomimetics.
• Antiviral & Antibiotic Development: Serves as a precursor for nucleoside analogs and other antimicrobial agents targeting pathogen-specific enzymes.
• Enzyme Inhibitor Synthesis: Employed in creating potent and selective glycosidase inhibitors for therapeutic and biochemical probing applications.
• Chemical Biology Probes: Utilized to build labeled carbohydrate probes for investigating biological recognition and signaling pathways.
• Process Chemistry: Acts as a validated starting material for scaling up the production of specialty fine chemicals under GMP-like conditions.

Basic Information

Item	Details
Product Name	D-Galactitol, 2-Deoxy-2-(1,1-Dimethylethoxy)Carbonylamino-5,6-o-(1-Methylethylidene)-3-o-(Phenylmethyl)-1-o-(Triphenylmethyl)-, 4-Acetate
CAS No.	163707-60-6
Molecular Formula	C48H53NO9
Molecular Weight	787.94 g/mol
Synonyms	1,2,5,6-Di-O-isopropylidene-3-O-benzyl-4-O-acetyl-1-O-trityl-D-galactitol-2-yl carbamate, tert-Butyl ester; 2-Deoxy-2-[(tert-butoxycarbonyl)amino]-5,6-O-isopropylidene-3-O-benzyl-1-O-trityl-D-galactitol-4-acetate; Boc-protected galactitol derivative; Galactitol building block, Boc, Bn, Trt, Ac, isopropylidene protected; 1-O-Trityl-3-O-benzyl-4-O-acetyl-5,6-O-isopropylidene-D-galactitol-2-yl N-(tert-butoxycarbonyl)carbamate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity, essential for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and scale-up needs with custom synthesis and specification tailoring upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccant packs or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.