Description

D-Glucitol, 2-Deoxy-2-(1,1-Dimethylethoxy)Carbonylamino-5,6-o-(1-Methylethylidene)-3-o-(Phenylmethyl)-1-o-(Triphenylmethyl)- CAS NO 163707-56-0 is a sophisticated, multi-protected carbohydrate derivative, specifically designed as a key chiral intermediate in advanced organic synthesis. Its complex protective group pattern provides orthogonal reactivity, enabling selective deprotection and functionalization at specific hydroxyl positions. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of complex glycoconjugates, nucleoside analogs, and other bioactive molecules requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel antiviral agents, nucleoside analogs, and complex carbohydrate-based therapeutics.
• Glycochemistry Research: Used in the development of glycosylation methodologies and the construction of complex oligosaccharide structures for biological studies.
• Chiral Pool Synthesis: Serves as a valuable source of chirality for the asymmetric synthesis of natural products and other high-value compounds.
• Protecting Group Strategy: Demonstrates the application of trityl (Tr), benzyl (Bn), and isopropylidene (acetonide) protecting groups in multi-step synthetic sequences.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, catalysts, and ligands where specific sugar scaffolds are required.
• Process Development: Used in route scouting and optimization for the scalable production of carbohydrate-derived active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	D-Glucitol, 2-Deoxy-2-(1,1-Dimethylethoxy)Carbonylamino-5,6-o-(1-Methylethylidene)-3-o-(Phenylmethyl)-1-o-(Triphenylmethyl)-
CAS No.	163707-56-0
Molecular Formula	C46H49NO7
Molecular Weight	727.89 g/mol
Synonyms	1-O-Trityl-3-O-benzyl-5,6-O-isopropylidene-2-deoxy-2-[(tert-butoxycarbonyl)amino]-D-glucitol; 2-Deoxy-2-[(tert-butoxycarbonyl)amino]-5,6-O-isopropylidene-3-O-benzyl-1-O-trityl-D-glucitol; Boc-protected glucitol derivative; Protected D-glucitol intermediate; tert-Butyl N-[(1S,2R,3R,4R,5R)-4,5-bis(benzyloxy)-1-[(trityloxy)methyl]-6,8-dioxabicyclo[3.2.1]octan-3-yl]carbamate (isomeric representation); Carbohydrate building block 163707-56-0; Multifunctional sugar derivative.
EINECS	Contact for details

Quality Control

This high-value synthetic intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity essential for research and process chemistry. Our rigorous analytical testing includes HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch. We adhere to cGMP principles where applicable to support its use in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.