Description

2,4,4'-Trihydroxychalcone is a polyphenolic chalcone derivative with significant biological and chemical activity. This compound matters as a versatile synthetic intermediate and a promising bioactive scaffold for research and development. It is primarily needed by the pharmaceutical, nutraceutical, and cosmetic industries for applications in drug discovery, antioxidant formulations, and as a reference standard for analytical purposes.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or lead compound in the synthesis of novel therapeutic agents targeting inflammation, oxidative stress, and metabolic disorders.
• Nutraceutical & Dietary Supplements: Utilized as a potent antioxidant ingredient due to its polyphenolic structure, contributing to formulations aimed at promoting cellular health.
• Cosmetic & Personal Care: Incorporated into anti-aging and skin-protective products for its potential to neutralize free radicals and protect against environmental stressors.
• Biochemical Research: Acts as a reference standard or inhibitor in enzymatic studies, particularly those involving tyrosinase or other oxidoreductases.
• Material Science: Investigated for its potential in developing novel organic dyes, UV-absorbing materials, or metal-chelating agents.
• Food Science: Studied for its natural preservative and antioxidant properties to enhance the shelf-life and nutritional quality of food products.

Basic Information

Product Name	2,4,4'-Trihydroxychalcone
CAS No.	163121-02-6
Molecular Formula	C₁₅H₁₂O₄
Molecular Weight	256.25 g/mol
Synonyms	2',4,4'-Trihydroxychalcone; (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one; 3-(4-Hydroxyphenyl)-1-(2,4-dihydroxyphenyl)-2-propen-1-one; 2,4,4'-Trihydroxy-trans-chalcone; NSC 407291; Chalcone, 2',4,4'-trihydroxy-
EINECS	Contact for details

Quality Control

Our 2,4,4'-Trihydroxychalcone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity research-grade standards. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.