Description

2-(tert-Butyldimethylsilyl)Thiophene is a high-value organosilicon-protected thiophene derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile synthetic intermediate, where the tert-butyldimethylsilyl (TBDMS) group acts as a robust protecting group for sensitive functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, enabling the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those containing thiophene or heterocyclic cores.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the thiophene moiety imparts specific biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport or emissive layer materials in advanced display technologies.
• Polymer & Material Science: Monomer or modifier for creating conductive polymers and specialty materials with tailored electronic properties.
• Cross-Coupling Reactions: Effective substrate in palladium-catalyzed reactions like Suzuki, Stille, or Negishi couplings for carbon-carbon bond formation.
• Academic & R&D: Fundamental reagent in methodological development and exploratory chemistry within university and corporate research laboratories.

Basic Information

Product Name	2-(tert-Butyldimethylsilyl)Thiophene
CAS No.	163079-25-2
Molecular Formula	C10H18SSi
Molecular Weight	198.40 g/mol
Synonyms	2-(tert-Butyldimethylsilyl)thiophene; 2-(Tert-Butyldimethylsilyl)thiophene; 2-TBDMS-Thiophene; Thiophene, 2-[(1,1-dimethylethyl)dimethylsilyl]-; 2-[(tert-Butyldimethylsilyl)]thiophene; 2-(tert-Butyl-dimethyl-silanyl)-thiophene; 2-(tert-Butyldimethylsilanyl)thiophene
EINECS	Contact for details

Quality Control

Every batch of 2-(tert-Butyldimethylsilyl)Thiophene is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can compromise product integrity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.