Description

(Z)-Methyl 2-Iodo-3-Methoxyacrylate is a high-value, functionalized iodoacrylate ester that serves as a versatile building block in advanced organic synthesis. Its core value lies in its ability to introduce both an electrophilic iodine atom and a reactive acrylate moiety, enabling efficient carbon-carbon and carbon-heteroatom bond formation. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to construct complex molecular architectures for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of heterocyclic compounds, enzyme inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Cross-Coupling Reactions: Precursor in palladium-catalyzed reactions such as Heck, Suzuki, and Sonogashira couplings to form complex olefins.
• Material Science Research: Monomer or modifier for creating polymers with specific optical or electronic properties.
• Chemical Biology Probes: Used in the synthesis of activity-based probes or labeled compounds for studying biological pathways.
• Academic & R&D: A valuable reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	(Z)-Methyl 2-Iodo-3-Methoxyacrylate
CAS No.	163041-47-2
Molecular Formula	C7H9IO3
Molecular Weight	268.05 g/mol
Synonyms	Methyl (Z)-2-iodo-3-methoxyacrylate; Methyl (Z)-3-methoxy-2-iodoacrylate; (Z)-Methyl 3-methoxy-2-iodo-2-propenoate; 2-Iodo-3-methoxyacrylic acid methyl ester (Z-isomer); Methyl α-iodo-β-methoxyacrylate; (Z)-2-Iodo-3-methoxyacrylic Acid Methyl Ester; Methyl (Z)-α-iodo-β-methoxyacrylate
EINECS	Contact for details

Quality Control

Our (Z)-Methyl 2-Iodo-3-Methoxyacrylate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We are committed to consistent quality and supply reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
(Z)-Isomer Content (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.