Description

Cyclopropanecarboxylic Acid, 1-(Carboxyamino)-, Monomethyl Ester (9Ci) is a specialized, high-purity chemical intermediate with a unique cyclopropane ring structure. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, offering chemists a versatile scaffold for further functionalization. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular architecture is paramount. Its defined stereochemistry and functional groups make it an essential reagent for advanced medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) or metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the cyclopropane moiety can contribute to biological activity and stability.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical spaces and reaction pathways.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex organic molecules during process development.
• Ligand and Catalyst Preparation: Potential precursor for the synthesis of chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-(Carboxyamino)-, Monomethyl Ester (9Ci)
CAS No.	162873-03-2
Molecular Formula	C7H11NO4
Molecular Weight	173.17 g/mol
Synonyms	1-(Carboxyamino)cyclopropanecarboxylic acid monomethyl ester; Methyl 1-(carboxyamino)cyclopropanecarboxylate; 1-Aminocarbonylcyclopropanecarboxylic acid methyl ester; Cyclopropanecarboxylic acid, 1-[(methoxycarbonyl)amino]-; (1-(Methoxycarbonylamino)cyclopropyl)formic acid (theoretical); 1-Carbamoylcyclopropanecarboxylic acid methyl ester (related); CAS 162873-03-2
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 1-(Carboxyamino)-, Monomethyl Ester (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We support development and cGMP manufacturing needs with documentation suitable for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.